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崔秀坤
2015-02-27 10:56  
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崔秀坤

(信息截止2018年3月31日)

1、个人简介:2013年于华中科技大学获遗传学博士学位,同年7月进入伟德国际BETVLCTOR工作。参与医学院本科生和研究生的医学细胞生物学和医学遗传学的主讲工作。主要从事眼科遗传病致病机理研究及相关药物靶向研发工作。

2、承担的研究项目:主持国家自然科学基金项目青年基金1项(81400387),面上项目1项(81770911),参与国家自然科学基金3项(第一参与人)。

3、已发表论文:目前发表SCI论文 17篇,其中第一作者10篇(JCR 2区5篇)。

(1)Cui Xiukun#, Zhou Zheng#, Zhu Keke#,et al.,A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.DNA Cell Biol. 2018 Feb 28. [Epub ahead of print]

(2)Xiukun Cui,Wenxiu Han,Jing Li, et al.,Heat shock factor 4 regulates the expression of HSP25 and alphaB-crystallin by associating with DEXD/H-box RNA helicase UAP56.Cell Stress Chaperones. 2017 Nov 21.[Epub ahead of print]

(3)Xiu-Kun Cui#, Ke-Ke Zhu#, Zheng Zhou,et al.,A novel frameshift mutation in CX46 associated with hereditary dominant cataracts in a Chinese family.IntJ Ophthalmol2017;10(5):684-690.

(4)Cui Xiukun#,Liu Huiyuan#,Li Jing,et al.,Heat shock factor 4 regulates lens epithelial cell homeostasis by working with lysosome and anti-apoptosis pathways.,Int J Biochem Cell Biol,2016,79:118-127

(5)Cui Xiukun#, Xie Panpan, Jia Panpan,et al., Hsf4 counteracts Hsf1 transcription activities and increases lens epithelial cell survival in vitro. Biochimica et Biophysica Acta-Molecular Cell Research,2015, 1853(3):746-755.

(6) Zhang Jing#,Cui Xiukun#, Wang Lei,et al.,The mitochondrial thioredoxin is required for liver development in zebrafish. Curr Mol Med.2014;14(6):772-82.(Co-first)

(7)Xiukun Cui#, Lei Wang#, Jing Zhang#,et al., HSF4 Regulates DLAD Expression and Promotes Lens Denucleation. Biochim Biophys Acta-Molecular Basis of Disease, 1832 (2013) 1167-1172.

(8)Xiukun Cui#, Jing Zhang#, Du Rong#,et al., HSF4 is involved in DNA damage repair through regulation of Rad51. Biochim Biophys Acta-Molecular Basis of Disease 1822 (2012) 1308-1315.

(9)Xiukun Cui#, Feng Zeng#, Ying Liu,et al., A novel SCN1A missense mutation causes generalized epilepsy with febrile seizures plus in a Chinese family. Neurosci Lett 503 (2011) 27-30.

(10) Tailan Zhan#,Xiukun Cui#, Xuenong Xing,et al., Mucolipidosis in a Chinese family with compound heterozygous mutations at the GNPTAB gene. Clin Chim Acta 412 (2011) 1469-1471.(Co-first)

4、获奖情况:获得河南省科技进步二等奖1项(排名第二),河南省教育厅科技成果一等奖1项(排名第二)。

5、讲授课程:医学遗传学和医学细胞生物学

6、联系方式(邮箱等):xkcui@henu.edu.cn

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